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Alexandra I Zugno Selected Research

Guanidinoacetate N-Methyltransferase (Guanidinoacetate Methyltransferase)

9/2008Guanidinoacetate decreases antioxidant defenses and total protein sulfhydryl content in striatum of rats.
6/2007Guanidinoacetate inhibits glutamate uptake in rat striatum of rats at different ages.
5/2007Evidence that the inhibitory effects of guanidinoacetate on the activities of the respiratory chain, Na+,K+-ATPase and creatine kinase can be differentially prevented by taurine and vitamins E and C administration in rat striatum in vivo.
6/2003Inhibition of Na+, K+-ATPase activity in rat striatum by guanidinoacetate.

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Alexandra I Zugno Research Topics

Disease

20Schizophrenia (Dementia Praecox)
08/2021 - 08/2009
7Mania (Manias)
10/2013 - 04/2009
7Guanidinoacetate methyltransferase deficiency
09/2008 - 06/2003
5Homocystinuria
09/2003 - 04/2002
3Decapitation
02/2021 - 04/2012
3Bipolar Disorder (Manic Depressive Psychosis)
09/2013 - 06/2009
3Intellectual Disability (Idiocy)
12/2012 - 06/2004
2Body Weight (Weight, Body)
01/2021 - 04/2012
2Tyrosinemias (Tyrosinemia)
11/2018 - 12/2012
2Sepsis (Septicemia)
01/2015 - 01/2010
2Neurobehavioral Manifestations
09/2013 - 11/2012
2Epilepsy (Aura)
03/2006 - 06/2004
1Inflammation (Inflammations)
02/2021
1Mental Disorders (Mental Disorder)
01/2020
1Infections
01/2018
1Neurodevelopmental Disorders
01/2015
1Fructose Intolerance (Intolerance, Fructose)
12/2014
1Inborn Genetic Diseases (Disease, Hereditary)
12/2012
1Cerebral Malaria
08/2012
1Neurodegenerative Diseases (Neurodegenerative Disease)
08/2012
1Weight Gain
06/2012
1Obesity
06/2012
1Maple Syrup Urine Disease
04/2012
1Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis)
03/2012
1Tendinopathy (Tendonitis)
01/2012
1HIV Infections (HIV Infection)
06/2011
1Mitochondrial Diseases (Mitochondrial Disease)
03/2011
1Depressive Disorder (Melancholia)
09/2009
1Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
12/2008
1Lesch-Nyhan Syndrome (Choreoathetosis Self Mutilation Hyperuricemia Syndrome)
02/2004

Drug/Important Bio-Agent (IBA)

20KetamineFDA LinkGeneric
08/2021 - 08/2009
11AcetylcholinesteraseIBA
04/2017 - 06/2003
7Adenosine Triphosphatases (ATPase)IBA
04/2009 - 04/2002
7glycocyamineIBA
09/2008 - 06/2003
6EnzymesIBA
11/2018 - 06/2002
6CreatineIBA
09/2008 - 06/2004
5Cholinergic Agents (Cholinergics)IBA
11/2018 - 09/2013
4Guanidinoacetate N-Methyltransferase (Guanidinoacetate Methyltransferase)IBA
09/2008 - 06/2003
3AntioxidantsIBA
01/2021 - 09/2008
3SmokeIBA
01/2017 - 11/2011
3Brain-Derived Neurotrophic Factor (BDNF)IBA
08/2015 - 08/2012
3LithiumIBA
09/2013 - 04/2009
3Valproic Acid (Depakote)FDA LinkGeneric
09/2013 - 04/2009
3Dextroamphetamine (Dexedrine)FDA LinkGeneric
09/2013 - 04/2011
3Creatine Kinase (Creatine Phosphokinase)IBA
04/2011 - 09/2009
3HomocysteineIBA
09/2003 - 06/2002
2Folic Acid (Vitamin M)FDA LinkGeneric
08/2021 - 10/2016
2Ascorbic Acid (Vitamin C)FDA LinkGeneric
02/2021 - 04/2017
2CytokinesIBA
02/2021 - 01/2012
2Antipsychotic Agents (Antipsychotics)IBA
01/2021 - 06/2012
2Tyrosine (L-Tyrosine)FDA Link
11/2018 - 12/2012
2Butyric Acid (Butanoic Acid)IBA
10/2013 - 12/2011
2Acetylcholine (Acetylcholine Chloride)FDA Link
09/2013 - 09/2013
2Dopamine (Intropin)FDA LinkGeneric
09/2013 - 06/2012
2Glutamic Acid (Glutamate)FDA Link
09/2013 - 06/2007
2Cholinesterases (Cholinesterase)IBA
06/2013 - 09/2003
2Therapeutic UsesIBA
01/2012 - 12/2008
2Methionine (L-Methionine)FDA Link
09/2003 - 06/2002
1MethyltransferasesIBA
08/2021
1Interleukin-10 (Interleukin 10)IBA
02/2021
1Haloperidol (Haldol)FDA LinkGeneric
01/2021
1MelatoninIBA
01/2020
1Immunomodulating AgentsIBA
01/2020
1Biological ProductsIBA
01/2020
1Tyrosine Transaminase (Tyrosine Aminotransferase)IBA
11/2018
1AcidsIBA
04/2018
1Clozapine (Clozaril)FDA LinkGeneric
04/2018
1KynurenineIBA
02/2018
1Nerve Growth Factors (Neurotrophins)IBA
08/2015
1InterleukinsIBA
08/2015
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
08/2015
1Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
01/2015
1FructoseIBA
12/2014
1SugarsIBA
12/2014
1Rivastigmine (Exelon)FDA LinkGeneric
09/2013
1Neurotransmitter Agents (Neurotransmitter)IBA
09/2013
1Cholinesterase Inhibitors (Anticholinesterases)IBA
09/2013
1Messenger RNA (mRNA)IBA
12/2012
1Histamine Receptors (Histamine Receptor)IBA
06/2012
1Olanzapine (Zyprexa)FDA Link
06/2012
1Serotonin (5 Hydroxytryptamine)IBA
06/2012
1IceIBA
04/2012
1Bupropion (Wellbutrin)FDA LinkGeneric
04/2012
1Pharmaceutical PreparationsIBA
01/2012
1Diclofenac (SR 38)FDA LinkGeneric
01/2012
1GoldIBA
01/2012
1Histone Deacetylase InhibitorsIBA
12/2011
1DNA (Deoxyribonucleic Acid)IBA
11/2011
1TamoxifenFDA LinkGeneric
04/2011
1Anesthetics (Anesthetic Agents)IBA
11/2010
1Free RadicalsIBA
01/2010
1Antidepressive Agents (Antidepressants)IBA
09/2009
1Proteins (Proteins, Gene)FDA Link
08/2009
1Amphetamine (Amfetamine)FDA LinkGeneric
06/2009
1Methylphenidate (Ritalin)FDA LinkGeneric
12/2008
1Sulfhydryl Compounds (Thiols)IBA
09/2008
1Uric Acid (Urate)IBA
02/2004
1XanthineIBA
02/2004

Therapy/Procedure

1Intraperitoneal Injections
08/2021
1Highly Active Antiretroviral Therapy (HAART)
06/2011